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IK1 inhibitor PA-6
CAS No. 500715-03-7
IK1 inhibitor PA-6 ( —— )
产品货号. M22001 CAS No. 500715-03-7
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥275 | 有现货 |
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| 5MG | ￥437 | 有现货 |
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| 10MG | ￥851 | 有现货 |
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| 25MG | ￥1604 | 有现货 |
|
| 50MG | ￥2722 | 有现货 |
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| 100MG | ￥3993 | 有现货 |
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| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称IK1 inhibitor PA-6
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.
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产品描述IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
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同义词——
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通路Cell Cycle/DNA Damage
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靶点Potassium Channel
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受体KIR2.x currents
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研究领域——
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适应症——
化学信息
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CAS Number500715-03-7
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分子量492.62
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分子式C31H32N4O2
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纯度>98% (HPLC)
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溶解度DMSO:120mg/ml (243.59 Mm; Need ultrasonic)
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SMILESN=C(NC1=CC=C(OCCCCCOC2=CC=C(NC(=N)C3=CC=CC=C3)C=C2)C=C1)C1=CC=CC=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ji Y, et al. The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. Br J Pharmacol. 2017 Aug;174(15):2576-2590.2. Ji Y, et al. PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression. J Biomed Sci. 2017 Jul 15;24(1):44.
产品手册
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